Adrenal Fatigue ⁃ be careful with saliva tests
- HPA axis dis regulation
- HPA AXIS – key
- Governs reaction to stress
- Very impacted by stress
- Cortisol is key hormone
- Homeostasis disturbed in stress
- Blood pressure , blood sugar are all affected
4 key drivers
- Perceived stress
- Blood sugar dis regulation
- Circadian disruption ( 24 hr rhythm ) — blue light, travel and jet lag, sleep deprivation and lack of vitamin D ( sunlight )
- Inflammation of any kind ( stresses HPA axis ) including microbiome issues, food allergies , food and chemical toxin exposure
- Not a sound concept about how adrenals stop producing cortisol and DHEA
- HPA dysfunction is the key
- Not actually low cortisol
BRAIN – key not just adrenals
- Cellular resistance to cortisol
- Decreased receptivity to cortisol !!!
- Hence cortisol stays high
- Limited to free cortisol
- Not best marker
- Most is secreted in urine as metabolite
Dutch Urine Test
- Precision analytical lab
- Best test
- “Dried urine total cortisol hormone test “
- Eliminates discrepancies
- Most accurate test
Brain and local tissue response is what drives cortisol problems not just the adrenals !!
HPA axis dysfunction
- Perceived Stress
- New, unpredictable, threat sense of what’s happening to us
- Circadian disruption
- Blood sugar disruption
- Lack of exercise
- Inflammation – cytokines can raise cortisol levels. The body pumps up cortisol to deal with inflammation. If the inflammation is chronic – cortisol keeps getting released. This leads to cortisol resistance or down regulation of HPA axis.
- Sleep deprivation
- Poor memory
- Brain fog
- Postural hypotension
- Cold and flus
- Cold hands and feet
- Tachycardia in am
Chronic disease affected by HPA axis regulation:
- Chronic fatigue syndrome
- Gut microbiome – inflammation – HPA axis involved – inflammation – continuous cycle
Thoughts – huge player on stress response. It’s how the stress is perceived. Is it a threat or a challenge ?
Sense of urgency is a factor – do we need to address it right away ? Can it wait ?
Expand your time horizon.
Recognize that not all stress is harmful.
Diet and lifestyle changes to help HPA axis:
- Blood sugar
- Exercise ( over or under )
- Sleep deprivation
- Negative thoughts
- Lack of relationships
- Money problems
- Unresolved conflicts
1. Dutch Urine Test
- Total cortisol
3. Using strategies that quiet sympathetic nervous system- meditation / deep breathing.
4. Diet, sleep , social support, exercise
5. Often people lack knowledge and motivation.
See Paleo Rehab Program